| 发明名称 |
3,3 DISUBSTITUTED 19-NOR PREGNANE COMPOUNDS, COMPOSITIONS, AND USES THEREOF |
| 摘要 |
Provided herein are 3,3-disubstituted 19-nor- steroidal compounds according to Formula (I) and (III): where R1,R2, R3, R3', R4, R6a, R6a, R11a, and R11b are as defined herein. Compounds of the present invention are contemplated useful for the prevention and treatment of a variety of CNS-related conditions, for example, treatment of sleep disorders, mood disorders, insomnia, anxiety, depression, traumatic brain injury (TBI), stress, and epilepsy. |
| 申请公布号 |
WO2013056181(A1) |
申请公布日期 |
2013.04.18 |
| 申请号 |
WO2012US60136 |
申请日期 |
2012.10.12 |
| 申请人 |
SAGE THERAPEUTICS, INC. |
发明人 |
UPASANI, RAVINDRA, B.;ASKEW, BENNY, C.;HARRISON, BOYD, L.;DISTEFANO, PETER, SCOTT;SALITURO, FRANCESCO, G.;ROBICHAUD, ALBERT, J. |
| 分类号 |
C07J5/00;A61K31/57;A61K31/573;A61K31/58;A61P25/00;C07J7/00;C07J31/00;C07J43/00 |
主分类号 |
C07J5/00 |
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