发明名称 |
Hyaluronic Acid Decomposition-Promoting Factor and Inhibitor Thereof |
摘要 |
The present invention is directed to KIAA1199, which is a novel factor involved in decomposition of hyaluronic acid, and to use thereof. More specifically, the invention is directed to a hyaluronic acid decomposition-promoting agent containing the KIAA1199 gene and a protein encoded by the gene; to a hyaluronic acid decomposition-inhibiting agent characterized by inhibiting the activity or expression thereof (including an siRNA or a monoclonal antibody); and to a method for screening a novel hyaluronic acid decomposition-controlling agent, in which the method contains employing the expression of KIAA1199 as an index.
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申请公布号 |
US2013095110(A1) |
申请公布日期 |
2013.04.18 |
申请号 |
US201113701702 |
申请日期 |
2011.06.03 |
申请人 |
YOSHIDA HIROYUKI;INOUE SHINTARO;SAKAI SHINGO;NAGAOKA AYA;KAO CORPORATION |
发明人 |
YOSHIDA HIROYUKI;INOUE SHINTARO;SAKAI SHINGO;NAGAOKA AYA |
分类号 |
A61K39/395;A61K31/16;A61K31/198;A61K31/4015;A61K31/5415;A61K31/7048;A61K31/713;C07K7/08;C07K16/18;C12Q1/02 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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