| 发明名称 |
METHOD FOR PROVIDING HIGHER EFFECTIVENESS OF VIRAL TRANSDUCTION |
| 摘要 |
FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to biotechnology. Eukaryotic cells are transduced by retrovirus in the presence of the primer protein bis-meth-histone I 1.3. The method enables higher effectiveness of retroviral transduction and avoided disadvantages of the analogues.EFFECT: invention may be used in medicine, veterinary science, biology for producing drug preparations for in vitro/ex vivo gene therapy and gene modification of cells.6 dwg, 4 ex |
| 申请公布号 |
RU2478711(C1) |
申请公布日期 |
2013.04.10 |
| 申请号 |
RU20110151506 |
申请日期 |
2011.12.19 |
| 申请人 |
OTKRYTOE AKTSIONERNOE OBSHCHESTVO "INSTITUT STVOLOVYKH KLETOK CHELOVEKA" |
发明人 |
RIZVANOV AL'BERT ANATOL'EVICH;SOLOV'EVA VALERIJA VLADIMIROVNA;ISAEV ARTUR ALEKSANDROVICH;GENKIN DMITRIJ DMITRIEVICH |
| 分类号 |
C12N15/86;A61K48/00;C07K14/47 |
主分类号 |
C12N15/86 |
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