1,2,4-TRIAZINE-6-CARBOXAMIDE DERIVATIVE

摘要

A compound represented by general formula (I), or a salt thereof, having a Syk inhibitory effect. (In the formula, R1 represents a hydrogen atom or C1-C6 alkyl group optionally substituted by Ra; A represents a hydrogen atom, C1-C8 alkyl group optionally substituted by Ra, C2-C6 alkenyl group optionally substituted by Ra, C2-C6 alkynyl group optionally substituted by Ra, C3-C10 cycloalkyl group optionally substituted by Rb, C6-C14 aromatic hydrocarbon group optionally substituted by Rb, 4- to 10-membered unsaturated heterocyclic group optionally substituted by Rb, or 4- to 10-membered saturated heterocyclic group optionally substituted by Rb, or R1 and the nitrogen atoms that link these may together form a 4- to 10-membered unsaturated heterocycle or a 4- to 10-membered saturated heterocycle; R2 represents a hydrogen atom or C1-C6 alkyl group optionally substituted by Ra; and B represents an unsaturated heterocyclic group optionally substituted by Rc.)