| 发明名称 |
Tetrahydrophenanthridinones and tetrahydrocyclopentaquinolinones as PARP and tubulin polymerization inhibitors |
| 摘要 |
<p>The present invention provides compounds of formula (I), their use as inhibitors of tubulin polymerization and their use as PARP inhibitors as well as pharmaceutical compositions comprising said compounds of Formula (I) wherein R</p> |
| 申请公布号 |
AU2009228943(B2) |
申请公布日期 |
2013.04.04 |
| 申请号 |
AU20090228943 |
申请日期 |
2009.03.26 |
| 申请人 |
JANSSEN PHARMACEUTICA NV |
发明人 |
ROUX, BRUNO;MEYER, CHRISTOPHE;MEVELLEC, LAURENCE ANNE;ANGIBAUD, PATRICK RENE;VIALARD, JORGE EDUARDO;STORCK, PIERRE-HENRI |
| 分类号 |
C07D221/12;A61K31/473;A61P35/00;C07D401/06 |
主分类号 |
C07D221/12 |
| 代理机构 |
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