发明名称 |
CARRIER COMPOSITION FOR NUCLEIC ACID TRANSPORT |
摘要 |
<p>An object of the present invention is to provide a nucleic acid delivery carrier composition of low toxicity and high safety, the carrier composition, when used to administer a nucleic acid such as an siRNA into an animal-derived cell or organism, being capable of delivering efficiently the nucleic acids into the cells while protecting it from being degraded; and a nucleic acid deliver composition containing the carrier and a nucleic acid. The carrier composition for delivery of a nucleic acid is prepared by mixing (A) a cationic lipid having a steroid skeleton with (B) a tertiary ammonium salt-type cationic lipid. The nucleic acid delivery composition is prepared by mixing the nucleic acid delivery carrier with a nucleic acid.</p> |
申请公布号 |
EP1946761(B1) |
申请公布日期 |
2013.04.03 |
申请号 |
EP20060811872 |
申请日期 |
2006.10.17 |
申请人 |
OTSUKA PHARMACEUTICAL CO., LTD. |
发明人 |
TOYOBUKU, HIDEKAZU;MIYAO, HIDEO;SATO, MASAKO;SEKIGUCHI, KAZUO |
分类号 |
A61K31/7105;A61K9/127;A61K47/18;A61K47/28;A61K47/44;A61K47/48;A61K48/00;C12N15/88 |
主分类号 |
A61K31/7105 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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