发明名称 |
Heterobifunctional inhibitors of E-selectins and CXCR4 chemokine receptors |
摘要 |
Compounds, compositions and methods are provided for treating cancer and inflammatory diseases, and for releasing cells such as stem cells (e.g., bone marrow progenitor cells) into circulating blood and enhancing retention of the cells in the blood. More specifically, heterobifunctional compounds that inhibit both E-selectins and CXCR4 chemokine receptors are described.
|
申请公布号 |
US8410066(B2) |
申请公布日期 |
2013.04.02 |
申请号 |
US20100768173 |
申请日期 |
2010.04.27 |
申请人 |
MAGNANI JOHN L.;SARKAR ARUN K.;GLYCOMIMETICS, INC. |
发明人 |
MAGNANI JOHN L.;SARKAR ARUN K. |
分类号 |
A61K31/7036;C07H3/06;C07H15/207;C07H17/02 |
主分类号 |
A61K31/7036 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|