| 摘要 |
<p>A hydroxamic acid of formula (I) or a pharmaceutically acceptable salt thereof for use in a method for treating or preventing an immunological, inflammatory, autoimmune or allergic disorder or disease, or a transplant rejection, or a graft-versus host disease, or a neurogenerative disease, or neuron injury, where the symbols in formula (I) have the following meanings: X is aryl, heteroaryl, cycloalkyl or heterocyclyl, any of which is unsubstituted or substituted, or H; L is C1-C14 saturated alkylene or C2-C8-alkenylene, wherein the alkylene or alkenylene is unsubstituted or substituted, wherein one or two of the carbon atoms of the alkylene or alkenylene is replaced by NR', R' being hydrogen, alkyl, acyl, hydrogen, arylalkyl or, together with R, is (C1-C3)-alkylene, and wherein one or two of the carbon atoms of the alkylene or alkenylene is optionally replaced with O, S, S(O), S(O)2 or C(O); and R is H or, together with R', (C1-C3)-alkylene.</p> |
