发明名称 |
HETEROARYLOXY NITROGENOUS SATURATED HETEROCYCLIC DERIVATIVE |
摘要 |
Provided are compounds of a formula (I) and their pharmaceutically-acceptable salts:
wherein X1, X2 and X3 each independently represent N or CH; W represents the following formula (II):
or the following formula (III):
Y represents a group of a formula (IV):
The compounds have a histamine-H3 receptor antagonistic or inverse-agonistic activity and are useful for remedy and/or prevention of obesity, diabetes, hormone secretion disorders, sleep disorders, etc. |
申请公布号 |
EP1642898(B1) |
申请公布日期 |
2013.03.27 |
申请号 |
EP20040746741 |
申请日期 |
2004.06.24 |
申请人 |
MSD K.K. |
发明人 |
OHTAKE, NORIKAZU;NAYA, AKIRA;HAGA, YUJI;JITSUOKA, MAKOTO;SUGA, TAKUYA;YOSHIMOTO, RYO;TOKITA, SHIGERU;KANATANI, AKIO |
分类号 |
C07D401/12;A61K31/4545;A61K31/501;A61K31/506;A61P1/16;A61P3/00;A61P3/04;A61P3/06;A61P3/10;A61P7/00;A61P9/10;A61P9/12;A61P13/12;A61P19/06;A61P21/00;A61P25/00;A61P25/08;A61P25/16;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P25/30;A61P25/32;A61P25/36;A61P43/00;C07D401/14;C07D403/12;C07D405/14;C07D409/14;C07D413/14;C07D487/04 |
主分类号 |
C07D401/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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