| 摘要 |
<p>A bead based assay detection method (and apparatus) is for detecting an analyte, and using a device which comprises a substrate (50), a source region (S), a drain region (D) and a gate region, a channel region (65) between the source and drain regions and a nanopore passing through the substrate in electrical connection with the gate or channel region. A sample under test is drawn through the nanopore, and the sample under test comprises bioreceptors attached to a bead or a bead complex, in proportion to the presence of an analyte to be detected. A count of the beads or bead complexes is made based on modulation of a gate current.</p> |
