发明名称 |
Modified live (JMSO strain) Haemophilus parasuis vaccine |
摘要 |
The present invention is a culture of cells of Haemophilus parasuis exhibiting attenuated pathogenicity and capable of triggering a protective immune response when administered to pigs as a live vaccine. The present invention is also a method of preparing the cell culture, a method of preparing a vaccine from the cell culture, and a live vaccine based on the cell culture. The cell culture was modified from a pathogenic parent strain by MNNG mutagenesis and was selected by complete dependence on streptomycin for growth. |
申请公布号 |
US8404253(B2) |
申请公布日期 |
2013.03.26 |
申请号 |
US20060648390 |
申请日期 |
2006.12.28 |
申请人 |
OLIVEIRA SIMONE R.;SIMONSON RANDY R.;MAHLBERG JONATHAN D.;TITUS MARK D.;OLESON TRACY A.;NEWPORT LABORATORIES, INC. |
发明人 |
OLIVEIRA SIMONE R.;SIMONSON RANDY R.;MAHLBERG JONATHAN D.;TITUS MARK D.;OLESON TRACY A. |
分类号 |
A61K39/102;A01N63/00;A01N65/00;A61K48/00 |
主分类号 |
A61K39/102 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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