NOVEL ACRYLIC ACID DERIVATIVE

摘要

A compound represented by general formula (I) (in the formula, Ra represents an optionally substituted alkyl group, an optionally substituted alkenyl group, an optionally substituted cycloalkyl group, an optionally substituted aryl group, an optionally substituted saturated heterocyclyl group, or an optionally substituted unsaturated heterocyclyl group; Rb represents a hydrogen atom or an alkyl group; R1, R2, R5, and R6 represent a hydrogen atom, fluorine atom, or alkyl group; R4, R7, and R8 represent a hydrogen atom or alkyl group; and R3 and R9 represent a hydrogen atom or a prodrug group.), which has TAFIa enzyme inhibitory activity and is useful as a therapeutic drug for myocardial infarction, angina pectoris, acute coronary syndrome, stroke, deep vein thrombosis, pulmonary embolism, or the like; or a pharmacologically acceptable salt thereof.