Treatment of advanced solid tumors using combination of anti-ErbB3 immunotherapy and selected chemotherapy

摘要

Provided are methods and compositions for clinical treatment of solid tumors (e.g., advanced solid tumors) using anti-ErbB3 antibodies combined with a second agent selected from the group consisting of gemcitabine, carboplatin, pemetrexed, and cabazitaxel. Also provided are methods and compositions for clinical treatment of solid tumors using anti-ErbB3 antibodies combined with cetuximab and irinotecan.