PLURIPOTENT TENDON AND LIGAMENT PERIVASCULAR CELLS

摘要

The present invention relates to methods for the generation of pluripotent cells derived from tendon perivascular cells. Pluripotent cells can also be derived from ligament perivascular cells. These methods may involve the formation of tenospheres (i.e. cellular aggregates containing pluripotent-like cells derived from tendon and/or ligament). Accordingly, also methods for generating tenospheres are subject of the present invention. Furthermore, the present invention concerns pluripotent cells and/or tenospheres which can be obtained by the herein provided methods as well as methods for differentiating these pluripotent cells and/or tenospheres into a desired cell type.