| 发明名称 |
QUINAZOLINE BASED EGFR INHIBITORS CONTAINING A ZINC BINDING MOIETY |
| 摘要 |
The present invention relates to quinazoline containing zinc-binding moiety based derivatives of formula I that have enhanced and unexpected properties as inhibitors of epidermal growth factor receptor tyrosine kinase (EGFR-TK) and their use in the treatment of EGFR-TK related diseases and disorders such as cancer. |
| 申请公布号 |
KR20130028970(A) |
申请公布日期 |
2013.03.20 |
| 申请号 |
KR20137002341 |
申请日期 |
2007.09.10 |
| 申请人 |
CURIS, INC. |
发明人 |
QIAN CHANGGENG;CAI XIONG;GOULD STEPHEN;ZHAI HAIXIAO |
| 分类号 |
C07D239/86;A61K31/517;A61P35/00;C07D239/94 |
主分类号 |
C07D239/86 |
| 代理机构 |
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