TOLEROGENIC SYNTHETIC NANOCARRIERS FOR GENERATING CD8+REGULATORY T CELLS
摘要
Disclosed are synthetic nanocarrier methods, and related compositions, comprising administering MHC Class I-restricted and/or MHC Class II-restricted epitopes of an antigen and immunosuppressants in order to generate tolerogenic immune responses against the antigen, such as the generation of antigen- specific CD8+ regulatory T cells.
申请公布号
WO2012149282(A3)
申请公布日期
2013.03.14
申请号
WO2012US35405
申请日期
2012.04.27
申请人
SELECTA BIOSCIENCES, INC.;KISHIMOTO, TAKASHI, KEI;FRASER, CHRISTOPHER;MALDONADO, ROBERTO, A.
发明人
KISHIMOTO, TAKASHI, KEI;FRASER, CHRISTOPHER;MALDONADO, ROBERTO, A.