发明名称 |
Method of stabilizing and sterilizing peptides or proteins |
摘要 |
The present invention provides a method for sterilizing a protein-containing bioerodible implant. The sterilization is accomplished using &bgr;-radiation, or high energy electrons. Following sterilization the implant can be used in a variety of methods for the sustained release of a therapeutic protein to treat a disease or condition in a human or non-human subject. The sterilization process is compatible with proteins containing one or more disulfide bonds or easily oxidized methionine residues. |
申请公布号 |
AU2011292149(A1) |
申请公布日期 |
2013.03.14 |
申请号 |
AU20110292149 |
申请日期 |
2011.08.16 |
申请人 |
ALLERGAN, INC. |
发明人 |
LYONS, ROBERT T.;TROGDEN, JOHN T. |
分类号 |
A61L2/08;A61K9/00;A61K31/00;A61K47/00;A61L27/00 |
主分类号 |
A61L2/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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