ANTI DDR1 ANTIBODIES, THEIR USES AND METHODS IDENTIFYING THEM

摘要

An antibody that specifically binds to the extracellular domain of human discoidin domain receptor 1 (DDR1) outside the discoidin domain, and which reduces or blocks collagen- induced autophosphorylation of DDR1 without preventing collagen binding to DDR1. Preferably, the antibody binds to the DS-like domain of human DDR1.