HIGH YIELD YELLOW FEVER VIRUS STRAIN WITH INCREASED PROPAGATION IN CELLS
摘要
The invention provides a an inactive, non-replicating vaccine comprising whole virion, chemically inactivated Yellow Fever virus which is inactivated using a method that ensures preservation of critical, neutralizing epitopes. The Yellow Fever virus has been adapted to propagate in cells to higher yields than the unadapted virus. The invention also provides methods for preventing Yellow Fever viral infection.
申请公布号
EP2459709(A4)
申请公布日期
2013.03.13
申请号
EP20100804909
申请日期
2010.07.23
申请人
XCELLEREX, INC.
发明人
LEE, CYNTHIA, K.;MONATH, THOMAS, P.;GUERTIN, PATRICK, M.;HAYMAN, EDWARD, G.