摘要 |
<P>PROBLEM TO BE SOLVED: To provide a delayed release formulation for a drug for delivering to the colon. <P>SOLUTION: A delayed release coating comprising a mixture of a first material selected from starch; amylose; amylopectin; chitosan; chondroitin sulfate; cyclodextrin; dextran; pullulan; carrageenan; scleroglucan; chitin; curdulan and levan, and a second material which has a pH threshold at about pH 5 or above, is used to target release of a drug from a core to the intestine, particularly the colon. <P>COPYRIGHT: (C)2013,JPO&INPIT |