| 发明名称 |
DIAGNOSTIC AND THERAPEUTIC METHODS FOR CORNEAL ECTASIA FOLLOWING REFRACTIVE SURGERY, KERATOCONUS OR PELLUCID DEGENERATION |
| 摘要 |
The present invention relates to methods of diagnosis and treatment of corneal ectasia following refractive surgery, keratoconus or pellucid marginal degeneration in a subject by determining or modulating the level of expression of molecules associated with the Wnt signalling pathway. Marker molecules of the present invention include SFRP1, PITX2, LEF1, WNT16 and WNT5A.
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| 申请公布号 |
US2013058954(A1) |
申请公布日期 |
2013.03.07 |
| 申请号 |
US201013513800 |
申请日期 |
2010.12.02 |
| 申请人 |
SUTTON GERARD;MCAVOY JOHN;MADIGAN MICHELE;THE UNIVERSITY OF SYDNEY |
发明人 |
SUTTON GERARD;MCAVOY JOHN;MADIGAN MICHELE |
| 分类号 |
C40B30/00;A61K31/437;A61K31/5377;A61K31/7052;A61K33/00;A61K39/395;A61P27/02 |
主分类号 |
C40B30/00 |
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