发明名称 |
Methods for specifically selecting antibody-producing cells |
摘要 |
Methods are provided for selecting B cells that produce a desired antibody, comprising a step of culturing B cells, which have the properties of cell death being induced under specific conditions and that cell death being suppressed by a signal generated as a result of the binding between an antigen and an antibody expressed on B cell surface (B cell antigen receptor on the B cell surface), with an antigen under conditions in which cell death is induced, and selecting antibody-producing B cells that bind with the antigen as viable cells. |
申请公布号 |
US8389235(B2) |
申请公布日期 |
2013.03.05 |
申请号 |
US20060064324 |
申请日期 |
2006.08.29 |
申请人 |
OHMORI HITOSHI;KANAYAMA NAOKI |
发明人 |
OHMORI HITOSHI;KANAYAMA NAOKI |
分类号 |
C12P21/06;C12N5/00;C12N15/63 |
主分类号 |
C12P21/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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