<p>A 3-(a-methoxyl) methylene benzofuran-2(3H)-ketone synthesis method comprises the synthesis of O-hydroxy phenylacetic acid, the synthesis of lactone and the synthesis of an end product, with focus on lactone synthesis improvement, such that a three-step reaction is conducted in series without separating or purifying the intermediates - the O-hydroxy phenylacetic acid and the lactone.</p>