摘要 |
<p>The invention relates to compounds of formula (I):
<Chemistry id="chema01" num="0001"><Image id="ia01" he="46" wi="111" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" /></Chemistry>
where A is selected from:
<Chemistry id="chema02" num="0002"><Image id="ia02" he="37" wi="125" file="IMGA0002.TIF" imgContent="chem" imgFormat="TIFF" /></Chemistry>
and R<Sup>1</Sup>, R<Sup>2</Sup>, R<Sup>3</Sup>, R<Sup>4</Sup>, R<Sup>5</Sup>, R<Sup>10a</Sup>, R<Sup>10b</Sup>, M, Z, r and s are as defined in the description, useful for treating disorders mediated by acyl coA-diacylglycerol acyl transferase 1 (DGAT1), for example glucose tolerance, Type II diabetes or obesity. The invention also provides pharmaceutical compositions comprising such compounds.</p> |