| 发明名称 |
INDAZOLE COMPOUNDS USEFUL AS KETOHEXOKINASE INHIBITORS |
| 摘要 |
The present invention is directed to substituted indazole compounds of formula (I) pharmaceutical compositions of these compounds and methods of use thereof. The compounds of the present invention are ketohexokinase (KHK) inhibitors, useful for treating or ameliorating a KHK mediated metabolic disorders and/or diseases such as obesity, Type II diabetes mellitus and Metabolic Syndrome X. |
| 申请公布号 |
EP2560962(A1) |
申请公布日期 |
2013.02.27 |
| 申请号 |
EP20110718824 |
申请日期 |
2011.04.21 |
| 申请人 |
JANSSEN PHARMACEUTICA NV |
发明人 |
ZHANG, XUQING;ABAD, MARTA, C.;GIBBS, ALAN, C.;KUO, GEE-HONG;KUO, LAWRENCE, C.;SONG, FENGBIN;SUI, ZHIHUA |
| 分类号 |
C07D231/56;A61K31/416;A61K31/4745;A61K31/519;A61P3/04;A61P3/06;A61P3/10;A61P9/12;C07D401/04;C07D401/10;C07D401/12;C07D401/14;C07D403/10;C07D403/12;C07D471/04;C07D487/04;C07D487/10 |
主分类号 |
C07D231/56 |
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