发明名称 COMPOSITIONS APPLICABLE FOR ORAL ADMINISTRATION AND CONTAINING TRIAZOLO[4,5-d]PYRIMIDINE DERIVATIVE
摘要 FIELD: medicine, pharmaceutics.SUBSTANCE: present invention refers to chemical-pharmaceutical industry and represents a pharmaceutical composition containing: {1S-[1?,2?,3?(1S*,2R*),5?]}-3-(7-{[2-(34-difluorophenyl)cyclopropyl]amino)-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol; an excipient representing mixed mannitol and dibasic calcium phosphate dihydrate; a binding agent representing hydroxypropyl cellulose; a disintegrant representing sodium starch glycolate; and one or more lubricating agents.EFFECT: invention provides preparing the composition of the active compound possessing high stability and high bioavailability of the active agent.12 cl, 1 ex
申请公布号 RU2476223(C2) 申请公布日期 2013.02.27
申请号 RU20090104330 申请日期 2007.08.20
申请人 ASTRAZENEKA AB 发明人 BEHNKS SAJMON
分类号 A61K31/519;A61K9/20;A61K9/48 主分类号 A61K31/519
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