发明名称 |
Acyclic amine inhibitors of 5-methytioadenosine phosphorylase and nucleosidase |
摘要 |
The present invention relates to compounds of the general formula (I) which are inhibitors of 5′-methylthioadenosine phosphorylase or 5′-methylthioadenosine nucleosidase. The invention also relates to the use of these compounds in the treatment of diseases or conditions in which it is desirable to inhibit 5′-methylthioadenosine phosphorylase or 5′-methylthioadenosine nucleosidase including cancer, and to pharmaceutical compositions containing the compounds.
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申请公布号 |
US8383636(B2) |
申请公布日期 |
2013.02.26 |
申请号 |
US20070310597 |
申请日期 |
2007.09.07 |
申请人 |
INDUSTRIAL RESEARCH LIMITED;ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY;CLINCH KEITH;EVANS GARY BRIAN;FROHLICH RICHARD;FURNEAUX RICHARD HUBERT;KELLY PETER MICHAEL;MASON JENNIFER MARY;SCHRAMM VERN L.;TYLER PETER CHARLES;GULAB SHIVALL ASHWAH ASHWIN |
发明人 |
CLINCH KEITH;EVANS GARY BRIAN;FROHLICH RICHARD;FURNEAUX RICHARD HUBERT;KELLY PETER MICHAEL;MASON JENNIFER MARY;SCHRAMM VERN L.;TYLER PETER CHARLES;GULAB SHIVALL ASHWAH ASHWIN |
分类号 |
C07D487/04;A61K31/519;A61P35/00 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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