发明名称 |
MATERIAL AND METHOD FOR TREATING INTERNAL CAVITIES |
摘要 |
A hydrophilic biocompatible sustained-release material is disclosed. The material comprises amounts of Pluronic F-127, PEG-400, HPMC and water, effective to produce a composition of sufficiently low viscosity at room temperature to be injectable into an internal body cavity via a tube inserted within a urinary catheter. At body temperature, the material exhibits a much higher viscosity and will stably adhere to the internal surface of a body cavity. As the material dissolves, a therapeutic agent incorporated therein is slowly released to the body cavity, while the material itself is excreted from the body.
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申请公布号 |
US2013046275(A1) |
申请公布日期 |
2013.02.21 |
申请号 |
US201213553198 |
申请日期 |
2012.07.19 |
申请人 |
THERACOAT LTD.;HOLZER ASHER;DANIEL DORIT;MULLERAD MICHAEL;DE LA ZERDA JAIME;SHPOLANSKY URI;MALCHI NADAV;DOLLBERG YOSH;TAL DOR;YAVIN YOSSI;KONORTY MARINA |
发明人 |
HOLZER ASHER;DANIEL DORIT;MULLERAD MICHAEL;DE LA ZERDA JAIME;SHPOLANSKY URI;MALCHI NADAV;DOLLBERG YOSH;TAL DOR;YAVIN YOSSI;KONORTY MARINA |
分类号 |
A61K47/34;A61K31/16;A61K31/407;A61K31/704;A61K31/7068;A61M25/10;A61P1/00;A61P1/16;A61P9/00;A61P11/00;A61P13/02;A61P13/12;A61P15/00;A61P25/00 |
主分类号 |
A61K47/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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