COMBINATION OF PINITOL AND NATURAL PRODUCT FOR TREATING DIABETES MELLITUS

摘要

PURPOSE: A composition containing heme oxygenase-1 for regulating fibrosis in abdominal cavity is provided to enhance anti-EMT reaction and to suppress the fibrosis. CONSTITUTION: A composition for regulating fibrosis in abdominal cavity contains heme oxygenase-1(HO-1) protein as an active ingredient. The daily dose of the active ingredient(HO-1) is 0.0001-100 mg/kg(body weight). A vector contains a polynucleotide which expresses HO-1 protein. A pharmaceutical composition is manufactured in an injection formulation containing HO-1. The injection formulation is an isotonic aqueous solution or a suspension. [Reference numerals] (AA) Insulin(uU); (BB) Control group; (CC) Before injection; (DD) 3 days after injection; (EE) 2 weeks after injection; (FF) 4 weeks after injection; (GG) 8 weeks after injection