发明名称 |
Antibodies that specifically bind to A&bgr; oligomers and uses thereof |
摘要 |
The present inventors successfully produced monoclonal antibodies that are specific to only soluble A&bgr; oligomers, but do not recognize soluble A&bgr; monomers, which are physiological molecules. It was demonstrated that the antibodies are useful as diagnostic/therapeutic monoclonal antibodies for Alzheimer's disease.
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申请公布号 |
US8378081(B2) |
申请公布日期 |
2013.02.19 |
申请号 |
US20090533348 |
申请日期 |
2009.07.31 |
申请人 |
IMMUNAS PHARMA, INC.;NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY;MATSUBARA ETSURO;SHIBATA MASAO;YOKOSEKI TATSUKI |
发明人 |
MATSUBARA ETSURO;SHIBATA MASAO;YOKOSEKI TATSUKI |
分类号 |
C07K16/18;A61K39/395;C12P21/08 |
主分类号 |
C07K16/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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