发明名称 Compositions and methods for treatment of cancer
摘要 The present invention relates to pyrroloquinolinyl-pyrrole-2,5-dione compounds and pyrroloquinolinyl-pyrrolidine-2,5-dione compounds, and methods of preparation of these compounds. The present invention also relates to pharmaceutical compositions comprising pyrroloquinolinyl-pyrrole-2,5-dione compounds and pyrroloquinolinyl-pyrrolidine-2,5-dione compounds. The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a pyrroloquinolinyl-pyrrole-2,5-dione compound or pyrroloquinolinyl-pyrrolidine-2,5-dione compound of the present invention.
申请公布号 US8377927(B2) 申请公布日期 2013.02.19
申请号 US20100722394 申请日期 2010.03.11
申请人 ARQULE, INC.;LI CHIANG J.;ASHWELL MARK A.;HILL JASON;MOUSSA MAGDI M.;MUNSHI NERU 发明人 LI CHIANG J.;ASHWELL MARK A.;HILL JASON;MOUSSA MAGDI M.;MUNSHI NERU
分类号 A61P35/00;A61K31/55;C07D243/00 主分类号 A61P35/00
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