发明名称 BENZOMORPHOLINE DERIVATIVES AND METHODS OF USE
摘要 Selected benzomorpholine compounds are effective for prophylaxis and treatment of diseases, such as VEGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
申请公布号 CA2703257(C) 申请公布日期 2013.02.19
申请号 CA20082703257 申请日期 2008.10.28
申请人 AMGEN INC. 发明人 HARMANGE, JEAN-CHRISTOPHE;MARTIN, MATTHEW W.;TEFFERA, YOHANNES;SUBRAMANIAN, RAJU;WHITE, RYAN;ZANON, ROGER;LARROW, JAY;PAYACK, JOSEPH F.;DILMEGHANI SERAN, MINA
分类号 C07D413/14;A61K31/536;A61P35/00 主分类号 C07D413/14
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