发明名称 CHIRAL INTEGRIN MODULATORS AND METHODS OF USE THEREOF
摘要 The invention provides enantiomers of ajoene and derivtives of Z(-)-ajoene. The derivative of Z(-)-ajoene are useful for modulating integrin-mediated functions, for treating disorders, diseases or conditions in which integrins play a role, and for treating tissues to improve their condition for a subsequent use, such as transplantation.
申请公布号 CA2415985(C) 申请公布日期 2013.02.19
申请号 CA20012415985 申请日期 2001.07.10
申请人 BILLINGS PHARMACEUTICALS, INC. 发明人 DAVIDSON, JOHN B.;TATARINTSEV, ALEXANDER V.;TURGIEV, ALI S.;HILDRETH, JAMES E. K.
分类号 C07C321/12;C07C321/18;C07C323/65 主分类号 C07C321/12
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