Recombinant virus vector for gene introduction in lymphocyte

摘要

It is intended to provide a recombinant herpesvirus; a process for producing the same; and a pharmacological composition comprising a recombinant herpes virus. Further, it is intended to provide a vector comprising a herpesvirus genome gene and a BAC vector sequence; a cell comprising such a vector; a fragment capable of homologous recombination with herpesvirus genome; and a nucleic acid cassette comprising a BAC vector sequence. The objects have been attained by the development of a process for producing a recombinant herpesvirus in which use is made of a BAC vector sequence.