发明名称 PYRIDINE AND PYRIDINE DERIVATIVE AS mGluR2 ANTAGONIST
摘要 <P>PROBLEM TO BE SOLVED: To provide compounds to be used for treatment or prevention of psychosis, schizophrenia, Alzheimer's disease, cognitive disorders, memory deficits, colon cancer, sleep disturbance, circadian rhythm disorders, and glial tumors. <P>SOLUTION: The compounds are represented by formula (I). In the formula: one of X and Y is N while the other is CH, or both X and Y are N; A is aryl or 5 or 6 membered heteroaryl each of which is optionally substituted by 1C-6C alkyl; B is H, cyano or, is optionally substituted aryl or optionally substituted 5 or 6 membered heteroaryl. <P>COPYRIGHT: (C)2013,JPO&INPIT
申请公布号 JP2013028624(A) 申请公布日期 2013.02.07
申请号 JP20120203498 申请日期 2012.09.14
申请人 F HOFFMANN LA ROCHE AG 发明人 GATTI MCARTHUR SILVIA;GOETSCHI ERWIN;WICHMANN JUERGEN;WOLTERING THOMAS JOHANNES
分类号 C07D213/34;A61K31/44;A61K31/4436;A61K31/4439;A61K31/444;A61K31/4545;A61K31/505;A61K31/506;A61K31/5377;A61K31/541;A61P25/18;A61P25/20;A61P25/28;A61P35/00;A61P43/00;C07D213/53;C07D213/57;C07D213/71;C07D213/73;C07D239/26;C07D239/42;C07D401/04;C07D401/10;C07D401/14;C07D403/04;C07D403/14;C07D405/14;C07D409/10;C07D409/14;C07D413/04;C07D413/14;C07D417/04;C07D417/10;C07D417/14 主分类号 C07D213/34
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