There are provided methods and compositions for activating the expression of an exogenous gene by an exogenous integrase specifically in cells in which the exogenous integrase is expressed. The invention further relates to uses of the compositions in treatment of various conditions and disorders, as exemplified by selectively activating expression of a toxin only in target cell populations.
申请公布号
WO2013018096(A1)
申请公布日期
2013.02.07
申请号
WO2012IL50286
申请日期
2012.08.01
申请人
RAMOT AT TEL-AVIV UNIVERSITY LTD.;KOLOT, MIKHAIL;YAGIL, EZRA;MALCHIN, NATALIA