Disclosed herein are zinc fingers comprising CCHC zinc coordinating residues. Also described are zinc finger proteins and fusion proteins comprising these CCHC zinc fingers as well as polynucleotides encoding these proteins. Methods of using these proteins for gene editing and gene regulation are also described
申请公布号
AU2007334468(B2)
申请公布日期
2013.02.07
申请号
AU20070334468
申请日期
2007.12.13
申请人
SANGAMO BIOSCIENCES, INC.;DOW AGROSCIENCES LLC
发明人
BLUE, RYAN C.;PETOLINO, JOSEPH F.;URNOV, FYODOR;MILLER, JEFFREY;MITCHELL, JON C.;CAI, QIHUA C.;ARNOLD, NICOLE L.;BAKER, LISA W.;WORDEN, SARAH E.;GARRISON, ROBBI J.;SHUKLA, VIPULA K.