发明名称 |
TAMPER-RESISTANT TABLET PROVIDING IMMEDIATE DRUG RELEASE |
摘要 |
The invention relates to a tamper-resistant tablet comprising a matrix material in an amount of more than one third of the total weight of the tablet; and a plurality of coated particulates in an amount of less than two thirds of the total weight of the tablet; wherein said particulates comprise a pharmacologically active compound and a physiologically acceptable polymer, preferably a polyalkylene oxide; and form a discontinuous phase within the matrix material; which preferably provides under in vitro conditions immediate release of the pharmacologically active compound in accordance with Ph. Eur. |
申请公布号 |
CA2839123(A1) |
申请公布日期 |
2013.02.07 |
申请号 |
CA20122839123 |
申请日期 |
2012.07.27 |
申请人 |
GRUNENTHAL GMBH |
发明人 |
SCHWIER, SEBASTIAN;HAUPTS, MARCEL;BARNSCHEID, LUTZ;PATZ, JANA |
分类号 |
A61K9/20;A61K31/00 |
主分类号 |
A61K9/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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