发明名称 |
Process for preparing a fraction enriched with ginkgo terpenes |
摘要 |
Process for removing pesticides from Ginkgo biloba extracts, which involves submitting an extract obtained by conventional methods to the following steps:
a. Liquid-liquid extraction of the extract to obtain a medium polarity fraction containing ginkgo terpenes and pesticides not removable with hexane, and a high polarity fraction containing ginkgo flavone glycosides;
b. crystallisation from the medium polarity fraction obtained at step a) to give an intermediate with a ginkgolide content of not less than 50%;
c. crystallisation from the residual solution obtained at step b) to give an intermediate with a bilobalide content of not less than 50%;
d. mixing of the high polarity fraction obtained at step a) with the ginkgo terpene intermediate and the bilobalide intermediate obtained at steps b) and c). |
申请公布号 |
EP2554054(A1) |
申请公布日期 |
2013.02.06 |
申请号 |
EP20120190768 |
申请日期 |
2010.03.31 |
申请人 |
INDENA S.P.A. |
发明人 |
GIORI, ANDREA;MOMBELLI, GIACOMO;ARPINI, SABRINA;ACERBI, MARIO |
分类号 |
A23L1/015;A61K36/16 |
主分类号 |
A23L1/015 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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