COMBINATION VACCINE WITH WHOLE CELL PERTUSSIS ANTIGEN

摘要

PROBLEM TO BE SOLVED: To provide combination vaccines with a whole cell pertussis antigen.

SOLUTION: The vaccines include (a) D-T-Pw-HepB-Hib antigens and (b) one or more meningococcal conjugate antigens. A number of improvements and variations of these vaccines are discovered. The vaccines can be prepared extemporaneously at the time of use by mixing together two components: (a) a first component comprising D, T, wP and HBsAg antigens; and (b) a second component comprising a Hib conjugate and one or more meningococcal conjugates.

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