| 发明名称 |
PRODRUGS OF PHOSPHONATE NUCLEOTIDE ANALOGUES AND METHODS FOR SELECTING AND MAKING SAME |
| 摘要 |
An improved method for the use of magnesium alkoxide for the preparation of starting materials and compounds for use herein is provided. The method is useful for preparing compounds of structure (5a)
having substituent groups as defined herein which compounds can be used in antiviral therapy and prophylaxis. |
| 申请公布号 |
PL213214(B1) |
申请公布日期 |
2013.01.31 |
| 申请号 |
PL20010360490 |
申请日期 |
2001.07.20 |
| 申请人 |
GILEAD SCIENCES, INC. |
发明人 |
BECKER MARK W.;CHAPMAN HARLAN H.;CIHLAR TOMAS;EISENBERG EUGENE J.;HE GONG-XIN;KERNAN MICHAEL R.;LEE WILLIAM A.;PRISBE ERNEST J.;ROHLOFF JOHN C.;SPARACINO MARK L. |
| 分类号 |
C07H19/20;A61K31/664;A61K31/675;A61K31/7052;A61P31/12;A61P31/18;A61P35/00;C07F9/6561;C07H19/10;C07H21/00;C12Q1/18;G01N33/15;G01N33/50;G01N33/53 |
主分类号 |
C07H19/20 |
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