| 发明名称 |
KALLIKREIN 7 MODULATORS |
| 摘要 |
The present invention relates to the crystal structure of the serine protease kallikrein 7 and to the use of this crystal structure in drug discovery. The present invention also relates to compounds binding specifically to this active site of kallikrein 7.
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| 申请公布号 |
US2013028843(A1) |
申请公布日期 |
2013.01.31 |
| 申请号 |
US201213649089 |
申请日期 |
2012.10.10 |
| 申请人 |
NOVARTIS AG;NOVARTIS AG |
发明人 |
FLOHR STEFANIE;RANDL STEFAN ANDREAS;OSTERMANN NILS;HASSIEPEN ULRICH;BERST FREDERIC;BODENDORF URSULA;GERHARTZ BERND;MARZINZIK ANDREAS;EHRHARDT CLAUS;MEINGASSNER JOSEF GOTTFRIED |
| 分类号 |
C07D207/16;A61K31/40;A61K31/4025;A61K31/403;A61K31/4439;A61K31/445;A61K31/454;A61K31/472;A61K31/496;A61K31/5377;A61K49/00;A61P1/00;A61P1/18;A61P17/00;A61P17/02;A61P17/04;A61P17/06;A61P17/10;A61P29/00;A61P35/00;C07D209/52;C07D211/60;C07D217/26;C07D401/12;C07D403/12;C07D405/12;C07D409/12;C07D413/12;C12N9/50;C12N9/96;G01N21/64;G01N33/53;G06F17/50 |
主分类号 |
C07D207/16 |
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