发明名称 |
AZABENZIMIDAZOLE DERIVATIVE HAVING AMPK-ACTIVATING ACTIVITY |
摘要 |
Provided is a compound useful as an AMPK activator. A compound represented by formula (wherein R4 represents a hydrogen atom or a substituted or unsubstituted alkyl group; R1, R2 and R3 independently represent a hydrogen atom, a halogen atom, a hydroxy group, a cyano group, a nitro group, a carboxy group, a substituted or unsubstituted alkyl group, or the like, wherein a case in which R1, R2 and R3 represent a hydrogen atom simultaneously is excluded; X represents a single bond, -S-, -O-, -NR5-, -C(=O)-, or the like; R5 represents a hydrogen atom, or a substituted or unsubstituted alkyl group; and Y represents a substituted or unsubstituted cycloalkyl group, a substituted or unsubstituted cycloalkenyl group, a substituted or unsubstituted heterocyclyl group, or the like), or a pharmaceutically acceptable salt thereof. |
申请公布号 |
WO2013011932(A1) |
申请公布日期 |
2013.01.24 |
申请号 |
WO2012JP67889 |
申请日期 |
2012.07.13 |
申请人 |
SHIONOGI & CO., LTD.;KOJIMA, EIICHI;TONOGAKI, KEISUKE;TANAKA, NOBUYUKI;KATOU, MANABU;INO, AKIRA;IWATSU, MASAFUMI;FUJIOKA, MASAHIKO;HINATA, YU;OHYABU, NAOKI |
发明人 |
KOJIMA, EIICHI;TONOGAKI, KEISUKE;TANAKA, NOBUYUKI;KATOU, MANABU;INO, AKIRA;IWATSU, MASAFUMI;FUJIOKA, MASAHIKO;HINATA, YU;OHYABU, NAOKI |
分类号 |
C07D471/04;A61K31/437;A61K31/4545;A61K31/496;A61K31/5377;A61K31/675;A61P3/10;A61P43/00;C07F9/6561 |
主分类号 |
C07D471/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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