发明名称 |
Integrated instrument performing synthesis and amplification, and a system and method thereof |
摘要 |
An integrated instrument for oligonucleotide synthesis and PCR, and a system and method thereof are disclosed. The integrated instrument is basically composed of two independent modules. The first module is a unit for chemical de novo synthesis of oligonucleotides such as oligonucleotide primers and/or oligonucleotide hybridization probes. The second module is a unit for performing an analytical polymerase chain reaction amplification in real time, i.e. a qPCR. The two modules are operatively linked to each other in such a way that a user can load a nucleic sample to be analyzed into the integrated instrument and perform a PCR reaction by programming the instrument without a previous external synthesis of oligonucleotide amplification primers.
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申请公布号 |
US8357490(B2) |
申请公布日期 |
2013.01.22 |
申请号 |
US20100841708 |
申请日期 |
2010.07.22 |
申请人 |
ROCHE DIAGNOSTICS OPERATIONS, INC.;FROEHLICH THOMAS;GUTEKUNST MARTIN;HEINDL DIETER;ROESLER ANGELIKA;SEIBL RUDOLF |
发明人 |
FROEHLICH THOMAS;GUTEKUNST MARTIN;HEINDL DIETER;ROESLER ANGELIKA;SEIBL RUDOLF |
分类号 |
C12Q1/68;C12P19/34;C40B60/02;C40B60/04;C40B60/08 |
主分类号 |
C12Q1/68 |
代理机构 |
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