发明名称 DIAGNOSIS AND MONITORING OF ACUTE CORONARY SYNDROME
摘要 The disclosure provides methods and kits for diagnosing and monitoring inflammation and/or ischemia in an animal. The methods comprise determining the quantity of a post- translationally modified protein, other than phosphorylated tau, present in a body fluid from an animal. The disclosure also provides an improved method and kits for diagnosing appendicitis in an animal. The method comprises determining the quantities of orthohydroxyhippuric acid and of a marker of general inflammation, such as a post- translationally modified protein, present in one or more body fluids of the animal. The invention is directed to the diagnosis of ischemia by detection of cysteinylated proteins such as cysteinylated albumin. Binding partners and kits for this assay are claimed.
申请公布号 EP1587409(B1) 申请公布日期 2013.01.16
申请号 EP20030808141 申请日期 2003.10.02
申请人 DMI BIOSCIENCES, INC. 发明人 BAR-OR, DAVID;BAR-OR, RAPHAEL;WINKLER, JAMES, V.;YUKL, RICHARD, L.
分类号 C07K16/18;A61B;A61B1/00;A61B5/0402;C07K16/22;C07K16/26;C07K16/44;G01N33/48;G01N33/50;G01N33/53;G01N33/68;G01N33/74;G01N33/76 主分类号 C07K16/18
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