发明名称 |
DNA VACCINE COMBINED WITH AN INDUCER OF TUMOR CELL APOPTOSIS |
摘要 |
The present invention relates to the combination of a DNA vaccination strategy that makes use of a nucleic acid encoding a tumor antigen, with a non-immunosuppressive inducer of tumor cell differentiation and/or apoptosis or a tumor cell modifier, useful for cancer therapy. Vaccine compositions and kits are provided, as well as specific nucleic acid constructs that are particularly suitable for the preparation of such compositions. |
申请公布号 |
EP1496937(B1) |
申请公布日期 |
2013.01.16 |
申请号 |
EP20030717465 |
申请日期 |
2003.04.24 |
申请人 |
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) |
发明人 |
PADUA, ROSE ANN;CHOMIENNE, CHRISTINE;CHARRON, DOMINIQUE |
分类号 |
A61K39/00;C12N15/09;A61J1/05;A61K31/164;A61K31/203;A61K33/24;A61K38/00;A61K38/16;A61K39/39;A61K45/00;A61K45/06;A61K48/00;A61P35/00;A61P35/02;C07K16/30 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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