MICROFLUIDIC DEVICE WITH INTEGRATED SENSORS FOR CULTIVATION OF CELLS

摘要

The invention provides a microfluidic device (10) comprising a chamber (12) for holding at least one embryo (14), said chamber (12) enclosing a volume and comprising an inlet (13) and an outlet (13'), dimensioned for allowing said embryo (14) to enter and leave said chamber (12) and said chamber (12) adapted for holding a culture solution when said microfluidic device (10) is in operation, said chamber (12) further comprising at least one sensor (33, 33') integrated in said chamber (12) for in situ measuring of at least one selected from a chemical, physical and biochemical parameter of said culture solution when said microfluidic device (10) is in operation.