发明名称 TRANSFORMANT OF PLASMACYTOID DENDRITIC CELL PROPERTY LEUKEMIA CELL LINE AND USE OF THE SAME
摘要 <P>PROBLEM TO BE SOLVED: To provide a technique that reinforces a function that has already been provided and adds a new function to a plasmacytoid dendritic cell property leukemia cell line. <P>SOLUTION: A gene that codes a functional modulation protein CD80 that is a factor related to a costimulatory factor and/or a costimulatory signal is introduced to a plasmacytoid dendritic cell property leukemia cell line such as PMDC05 or the like, thereby the reinforcement of a function and the addition of a new function of the cell are made possible, and the reinforcement of an antigen-presenting capacity of a plasmacytoid dendritic cell property leukemia cell line, and the antigen presentation cell and a cytotoxic T-cell precursor cell are made to contact together, and the cytotoxic T-cell can be induced. <P>COPYRIGHT: (C)2013,JPO&INPIT
申请公布号 JP2013005756(A) 申请公布日期 2013.01.10
申请号 JP20110140566 申请日期 2011.06.24
申请人 NIIGATA UNIV 发明人 NARITA MIWAKO;TAKAHASHI MASUHIRO
分类号 C12N15/09;C12N5/10;C12Q1/02 主分类号 C12N15/09
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