| 发明名称 |
NOVEL SPIRO IMIDAZOLONE DERIVATIVES AS GLUCAGON RECEPTOR ANTAGONISTS, COMPOSITIONS, AND METHODS FOR THEIR USE |
| 摘要 |
The present invention relates to compounds of the general formula (I): wherein ring A, ring B, G, R3, Z, L1, and L2 are selected independently of each other and are as defined herein, to compositions comprising the compounds, and to methods of using the compounds as glucagon receptor antagonists and for the treatment or prevention of type 2 diabetes and conditions related thereto.
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| 申请公布号 |
US2013012493(A1) |
申请公布日期 |
2013.01.10 |
| 申请号 |
US201113636276 |
申请日期 |
2011.03.22 |
| 申请人 |
ZHAO HE;CHEN PING;LIN PEISHAN;DAI PENG;DAVIS JASON LOUIS;DEMONG DUANE E.;MILLER MICHAEL W.;DAI XING;WONG MICHAEL K.;LAVEY BRIAN J.;YU WENSHENG;ZHOU GUOWEI;STAMFORD ANDREW W.;KOZLOWSKI JOSEPH A.;GREENLEE WILLIAM J. |
发明人 |
ZHAO HE;CHEN PING;LIN PEISHAN;DAI PENG;DAVIS JASON LOUIS;DEMONG DUANE E.;MILLER MICHAEL W.;DAI XING;WONG MICHAEL K.;LAVEY BRIAN J.;YU WENSHENG;ZHOU GUOWEI;STAMFORD ANDREW W.;KOZLOWSKI JOSEPH A.;GREENLEE WILLIAM J. |
| 分类号 |
A61K31/454;A61K31/4178;A61K31/496;A61K31/5377;A61K31/5386;A61K31/55;A61P3/10;C07D401/14;C07D403/12;C07D403/14;C07D413/14;C07D498/08 |
主分类号 |
A61K31/454 |
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