摘要 |
The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein R1 is hydrogen or fluorine, one of A and B is R2, the other is a group -X-Y-R3. R3 represents a carbocyclic or heterocyclic ring. Further variables are as defined in the specification. Also claimed are- processes for their preparation, pharmaceutical compositions containing them and their use in therapy of diseases such as schizophrenia, cognitive disorders and pain by modulating the D-amino acid oxidase enzyme (DAAO). |
申请人 |
TAKEDA PHARMACEUTICAL COMPANY LIMITED;FARNABY, WILLIAM;FIELDHOUSE, CHARLOTTE;KERR, CATRINA;KINSELLA, NATASHA;LIVERMORE, DAVID;MERCHANT, KEVIN;MILLER, DAVID;HAZEL, KATHERINE |
发明人 |
FARNABY, WILLIAM;FIELDHOUSE, CHARLOTTE;KERR, CATRINA;KINSELLA, NATASHA;LIVERMORE, DAVID;MERCHANT, KEVIN;MILLER, DAVID;HAZEL, KATHERINE |